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Infectious Diseases >> SARS

Diagnosis

Laboratory confirmation of SARS-CoV infection is based on:

  • Detection of any of the following by a validated test, with confirmation in a reference laboratory:

    • Serum antibodies to SARS-CoV in a single serum specimen, or

    • A four-fold or greater increase in SARS-CoV antibody titer between acute- and convalescent-phase serum specimens tested in parallel, or

    • Negative SARS-CoV antibody test result on acute-phase serum and positive SARS-CoV antibody test result on convalescent-phase serum tested in parallel; or

  • Isolation in cell culture of SARS-CoV from a clinical specimen, with confirmation using a test validated by CDC; or

  • Detection of SARS-CoV RNA by RT-PCR validated by CDC, with confirmation in a reference laboratory, from:

    • Two clinical specimens from different sources, or

    • Two clinical specimens collected from the same source on two different days
       

 
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Bioinformatics Centre
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Mahatma Gandhi Institute of Medical Sciences, Sevagram - 442 102
 
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